Primary Myleofibrosis & The Jak Stat Pathway

    Over a year ago, my grandmother passed from PMF. I decided to do some research on the disease mechanisms, including the JAK STAT pathways. I had briefly learned about this pathway in biochemistry, but wanted a deeper dive into the disease. 

The attached table is all my work from working with the School of Pharmacy. 

Sources

Abdel-Wahab OI, Levine RL. Primary myelofibrosis: update on definition, pathogenesis, and treatment. Annu Rev Med. 2009;60:233-245. doi:10.1146/annurev.med.60.041707.160528

https://rarediseases.org/rare-diseases/primary-myelofibrosis/